Sunday, May 14, 2006

Recombinant human erythropoietin in a triplet pregnancy.


Title
Recombinant human erythropoietin in a triplet pregnancy: a case report.


Source
Journal of Reproductive Medicine. 50(11):863-6, 2005 Nov.


BACKGROUND:
Women carrying triplets are at greater risk for both anemia, due to the increased demands of the developingfetuses, and peripartum hemorrhage. Jehovah's witnesses are a unique obstetric population since women of this faith refuse blood transfusion.



CASE:
A Jehovah's Witness with a triplet pregnancy was successfully administered recombinant human erythropoietin (rHuEpo), 200 IU/kg 3 times per week subcutaneously, in order to correct her peripartum anemia. No side effects were observed during rHuEpo therapy, and the patient delivered healthy triplets.



CONCLUSION:
rHuEpo can be safely administered, with a beneficial effect in pregnancy, and seems to be an effective option in preventing transfusions as demonstrated in this case in a Jehovah's Witness.

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